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Which milk protein is known to be more difficult for neonates to digest?

  1. Casein

  2. Lysozyme

  3. Whey

  4. Albumin

The correct answer is: Casein

Casein is known to be more difficult for neonates to digest compared to other milk proteins. This is largely due to its structure and the way it coagulates in the stomach. Casein forms curds, which can be more challenging for the immature digestive systems of neonates to break down efficiently. Neonates have limited digestive enzyme activity, particularly when it comes to enzymes needed to break down proteins. Whey, on the other hand, is a more soluble protein that is easier to digest and is typically better tolerated by newborns. The presence of enzymes like lysozyme and the more easily digestible nature of whey make them more suitable for infant diets. Albumin, while present in milk, is also not a major protein component in the context of feeding infants when compared to casein and whey. The understanding of these proteins is essential for formulating infant nutrition, as it helps guide choices in breast milk versus formula and informs clinical decisions regarding feeding practices for neonates.